"In developing the potential drugs, Silverman and his team were able to produce something that pharmaceutical companies so far have not: highly selective compounds that inhibit the enzyme found in brain cells that produces nitric oxide but that do not affect similar nitric oxide-producing enzymes found in endothelial and macrophage cells."
Scientists have not tested the compounds on humans yet, but the initial animal trials appear promising:
"None of the fetuses born to animals treated with the two compounds died; more than half of those born to untreated animals died. Eighty-three percent of animals treated with one of the compounds were born normal, with no cerebral palsy characteristics. Sixty-nine percent of animals treated with the other compound were born normal."
This research greatly interests me because our son has cerebral palsy caused by a lack of oxygen at birth. Don't get me wrong, I love my son for who he is, but I am also in support of research that may help to minimize the long-term impacts of infant brain injury.
I'm with you! I think this sounds so promising.
ReplyDeleteEllen, thanks for the note. I also read your post on this topic. Definitely promising research!
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